Hesperegen™

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Hesperegen™ in Beauty Products

Molecular antioxidant | NRF2 activator | UV and aging protection

MOLECULAR INFORMATION

INCI: Hesperetin

CAS No. 520-33-2

EC No. 208-290-2

PRODUCT DESCRIPTION

Hesperegen™ is a next-generation citrus bioactive that delivers vitamin C benefits, at lower dosing by activating the natural antioxidant capacity of skin cells. Made through a cutting edge biocatalysis process, Hesperegen™ delivers bright and youthful skin at low use rates and easy formulation.
Unlike conventional antioxidants that neutralize free radicals directly, Hesperegen activates the body’s own defense system by triggering the Sirt1/Nrf2 pathways, master regulators of cellular antioxidant and detoxification genes. This results in longer-lasting protection and healthy, glowing skin.

EFFICACY

CONCLUSION

TECHNICAL INFORMATION

PRODUCT SPECIFICATIONS

Heavy metals: < 10 ppm

Globally approved for cosmetics

Microbial count: < 100 CFU/g

Specified pathogens: Absent

Appearance: White, free flowing powder

Loss on drying: < 3%

Identity by IR-spectroscopy: corresponds to reference spectrum

Content: > 95%

PRESERVATION AND MICROBIOLOGY

As a pure crystalline product, hesperegen™ doesn’t contain any preservative. Hesperegen™ is free of specified pathogens. The number of non-pathogenic microorganisms with less than 100 CFU per g of hesperegen™ meets the CTFA microbiology guidelines.

SAFETY AND ECOLOGY

The data available do not indicate any environmental risk. The manufacturing process is designed to meet the criteria for the assessment of safety, health and protection of people and of the environment set out in the Responsible Care Program.

PROCESSING AND DOSAGE

Recommended use level: 0.1%–1%
Solubility: Soluble in ethanol, glycols, emulsions
Stability: Heat and pH stable under typical formulation conditions
Regulatory Status: Available for cosmetic use in the U.S., EU, and Asia (pending region-specific approvals)

STORAGE AND SHELF LIFE

Hesperegen™ should be stored in the original sealed containers protected from light and humidity in a clean place at a temperature between 10 and 30°C. To avoid secondary microbial contamination, following opening, containers should be handled with special care. If stored under the recommended conditions, hesperegen™ remains stable for 2 years.

REMARK

Although these data and information have been prepared with the utmost possible care, we reserve the right to make changes due to product improvement and other considerations.

FORMULATION NOTES

Recommended use level: 0.1%–1%
Solubility: Soluble in ethanol, glycols, emulsions
Stability: Heat and pH stable under typical formulation conditions
Regulatory Status: Available for cosmetic use in the U.S., EU, and Asia (pending region-specific approvals)